| Greater Horizons | Kansas City | $15,000 | 3,279 | $1.9B |
| Greater Kansas City Community Foundation | Kansas City | $20,000 | 2,402 | $1.3B |
| St Louis Community Foundation Inc | St Louis | $20,000 | 1,375 | $302.0M |
| Community Foundation of the Ozarks Inc | Springfield | $15,050 | 970 | $66.3M |
| Veterans United Foundation | Columbia | $10,000 | 708 | $56.0M |
| Midway USA Foundation Inc | Columbia | $10,218 | 623 | $30.9M |
| Washington University | Saint Louis | $58,265 | 544 | $328.1M |
| United Way of Greater St Louis Inc | Saint Louis | $77,838 | 501 | $210.6M |
| St Louis Community Foundation | St Louis | $11,126 | 423 | $27.9M |
| United Way of Greater Kansas City Inc | Kansas City | $20,800 | 419 | $56.1M |
| Health Forward Foundation | Kansas City | $75,000 | 356 | $101.5M |
| Truman Heartland Community Foundation | Independence | $12,000 | 314 | $23.0M |
| Bass Pro Shops & Cabelas Outdoor Fund | Springfield | $15,000 | 258 | $23.6M |
| Regional Cultural and Performing Arts | St Louis | $15,000 | 247 | $16.2M |
| Youthbridge Community Foundation | Saint Louis | $20,400 | 244 | $50.2M |
| Southeast Missouri Food Bank Inc | Sikeston | $39,718 | 175 | $67.8M |
| Forvis Mazars Foundation | Springfield | $10,000 | 168 | $4.2M |
| Veterans of Foreign Wars of the United States | Kansas City | $44,622 | 154 | $41.6M |
| The Kansas City Royals Foundation | Kansas City | $15,000 | 149 | $6.6M |
| Ozarks Food Harvest Inc | Springfield | $68,498 | 148 | $142.3M |
| Leonard & Beryl Buck Foundation | Saint Louis | $100,000 | 144 | $133.4M |
| Jackson County Community Children's | Kansas City | $122,835 | 142 | $79.2M |
| Roman Catholic Foundation of Eastern | St Louis | $15,000 | 138 | $10.2M |
| Community Foundation of Central Mo | Columbia | $19,200 | 124 | $9.2M |
| Missouri Children's Trust Fund | Jefferson City | $67,155 | 113 | $36.1M |
| Mhm Support Services | Chesterfield | $15,000 | 112 | $5.0M |
| The Children's Mercy Hospital | Kansas City | $19,925 | 112 | $16.3M |
| Entrepreneur Startup Business | St Louis | $75,000 | 108 | $8.6M |
| Oracle Health Foundation | Kansas City | $11,545 | 108 | $21.3M |
| National Council of the US Society of | Maryland Heights | $13,292 | 101 | $6.2M |
| The Community Foundation of Northwest Missouriinc | Saint Joseph | $12,500 | 100 | $10.5M |
| Delta Dental of Missouri | St Louis | $25,000 | 97 | $5.2M |
| Theater League Inc | Kansas City | $10,000 | 97 | $14.4M |
| Bjc Health System | St Louis | $12,500 | 93 | $22.8M |
| Masonic Home of Missouri | Columbia | $9,000 | 91 | $2.1M |
| Missouri Humanities Council | Kansas City | $10,000 | 91 | $2.1M |
| United Way of Central Missouri Inc | Jefferson City | $29,000 | 91 | $7.7M |
| Government Employees Health Association Inc | Lees Summit | $10,000 | 84 | $6.1M |
| Community Capital Fund | Kansas City | $10,000 | 75 | $944K |
| Parents As Teachers National Center Inc | St Louis | $25,000 | 74 | $2.1M |
| Area Resources for Community | St Louis | $154,271 | 73 | $73.3M |
| Lockton Cares Inc | Kansas City | $15,400 | 72 | $1.9M |
| Regional Business Council | Saint Louis | $20,000 | 69 | $4.6M |
| Metropolitan Arts Council of | Kansas City | $5,500 | 67 | $1.3M |
| Ssm Health Care of Oklahoma Inc | St Louis | $20,000 | 66 | $4.2M |
| Ascension Seton | St Louis | $28,655 | 66 | $59.2M |
| Great Jobs Kc Inc | Kansas City | $254,172 | 66 | $89.3M |
| St John Medical Center Inc | St Louis | $80,000 | 65 | $26.9M |
| Missouri Sports Hall of Fame | Springfield | $13,559 | 64 | $2.7M |
| Extension Foundation | Kansas City | $45,287 | 63 | $12.6M |
| Restoring Lifeways | Kansas City | $25,000 | 62 | $3.7M |
| Generating Income for Tomorrow | Kansas City | $25,000 | 60 | $1.7M |
| Missouri United Methodist Foundation | Columbia | $14,790 | 58 | $3.4M |
| St John Health System Inc | St Louis | $10,000 | 57 | $5.7M |
| The Opportunity Trust | St Louis | $51,350 | 57 | $15.6M |
| National Rural Health Association | Kansas City | $14,656 | 56 | $6.5M |
| Staenberg Family Foundation | Saint Louis | $18,000 | 56 | $4.4M |
| Bjc Health System Group Return | St Louis | $10,000 | 56 | $9.5M |
| The Foundation for Barnes-Jewish | St Louis | $35,299 | 53 | $217.5M |
| The Global Orphan Project Inc | Kansas City | $28,951 | 53 | $4.8M |
| Boone Electric Community Trust | Columbia | $8,693 | 51 | $746K |
| After the Harvest | Kansas City | $11,836 | 51 | $10.2M |
| Ssm Health Care of Wisconsin Inc | St Louis | $19,835 | 50 | $3.0M |
| Northpoint Foundation Inc | Kansas City | $28,441 | 49 | $2.5M |
| Blues for Kids | St Louis | $13,572 | 48 | $2.2M |
| Head for the Cure Foundation | Kansas City | $15,000 | 47 | $3.3M |
| Mobile Health Clinics Association | St Louis | $12,500 | 47 | $726K |
| St Vincent Hospital and Health Care Center Inc | St Louis | $34,750 | 47 | $9.6M |
| School Smart Kc Inc | Kansas City | $52,500 | 47 | $21.3M |
| The Greater St Louis | St Louis | $10,000 | 46 | $812K |
| Combat Veterans Motorcycle Association | Liberty | $10,000 | 46 | $423K |
| Franklin County Area United Way Inc | Washington | $20,500 | 45 | $4.0M |
| Ascension Health Alliance | St Louis | $50,000 | 45 | $150.3M |
| St Louis Office for Developmental | Saint Louis | $92,082 | 44 | $23.4M |
| Perception Funding Inc | Kansas City | $26,717 | 43 | $4.6M |
| The Research Foundation | Kansas City | $25,000 | 43 | $2.5M |
| Pi Beta Phi Foundation | Town Country | $10,000 | 42 | $7.6M |
| Ssm Health Care Corporation | St Louis | $10,000 | 42 | $1.1M |
| Skaggs Foundation | Branson | $17,077 | 40 | $6.1M |
| St Vincent Health Inc | St Louis | $20,000 | 40 | $4.0M |
| St Louis Cardinals Community Fund | St Louis | $23,082 | 40 | $3.2M |
| Caring Communities Inc | Jefferson City | $10,000 | 40 | $2.3M |
| Esco Technologies Foundation | St Louis | $10,000 | 39 | $916K |
| Greater St Louis Inc | St Louis | $10,000 | 39 | $1.8M |
| Mercy Health Springfield Communities | Springfield | $10,600 | 39 | $1.3M |
| Missouri Association of Area Agencies on Aging | Jefferson City | $33,979 | 37 | $5.0M |
| Ssm Health Care St Louis | St Louis | $25,000 | 37 | $7.0M |
| Lake of the Ozarks Shootout Inc | Lake Ozark | $14,387 | 36 | $2.0M |
| Donald Danforth Plant Science Center | Saint Louis | $145,038 | 36 | $27.5M |
| Heart of Missouri United Way Inc | Columbia | $67,003 | 36 | $7.3M |
| Columbian Charities of Mo Inc | St Louis | $29,614 | 35 | $2.9M |
| St Mary's Health Inc | St Louis | $15,000 | 35 | $3.1M |
| Pkd Foundation | Kansas City | $80,000 | 35 | $7.0M |
| Heartland Regional Medical Center | St Joseph | $15,000 | 35 | $4.6M |
| Alliance for Life - Missouri Inc | Lees Summit | $32,034 | 35 | $7.8M |
| Downtown Kansas City Civic Ventures | Kansas City | $35,000 | 34 | $1.3M |
| Southeast Missouri Area Agency on | Cape Girardeau | $196,737 | 34 | $23.9M |
| Missouri Family Health Council Inc | Jefferson City | $247,206 | 34 | $29.8M |
| Bright Futures Fund | Kansas City | $105,188 | 33 | $10.3M |
| Disabled American Veterans | Kirksville | $10,000 | 32 | $809K |
| Saint Thomas West Hospital | St Louis | $16,000 | 32 | $17.7M |
| Seniorage Area Agency on Aging | Springfield | $60,931 | 31 | $7.0M |
| Donate Life Foundation | St Louis | $95,154 | 31 | $12.0M |
| Build-a-Bear Foundation Inc | Saint Louis | $34,620 | 30 | $5.2M |
| Mid America Assistance Coalition | Kansas City | $6,792 | 30 | $20.3M |
| Missouri Technology Corporation | St Louis | $200,000 | 30 | $44.4M |
| The St Louis Men's Group Against Cancer | St Louis | $8,000 | 30 | $957K |
| International Brotherhood of | Kansas City | $10,000 | 30 | $1.1M |
| One Classroom | St Louis | $13,500 | 29 | $959K |
| The Giving Branch Foundation | Columbia | $10,139 | 29 | $688K |
| Ascension Wisconsin Foundation Inc | St Louis | $96,843 | 28 | $16.7M |
| Young at Heart Resources | Cameron | $92,533 | 28 | $12.1M |
| Acruxkc | Kansas City | $12,500 | 27 | $1.3M |
| Mccarthy Holdings Charitable | St Louis | $16,250 | 27 | $1.3M |
| Missouri Baptist Foundation | Jefferson City | $12,986 | 26 | $695K |
| Freeman Health System | Joplin | $25,000 | 26 | $6.7M |
| Missouri Universal Service Fund | Jefferson City | $17,261 | 26 | $2.6M |
| Kansas City Soccer Foundation | Kansas City | $12,250 | 25 | $834K |
| Optimist International Foundation | St Louis | $10,528 | 25 | $712K |
| Mercy Hospitals East Communities | St Louis | $15,000 | 25 | $9.9M |
| The Home Builders Charitable Foundation | St Louis | $15,000 | 25 | $907K |
| Webster Electric Foundation | Marshfield | $10,000 | 25 | $403K |
| United Way of the Ozarks Inc | Springfield | $43,447 | 25 | $4.2M |
| Ascension Providence | St Louis | $20,500 | 25 | $2.8M |
| Missouri Organizing and Voter | St Louis | $73,300 | 25 | $3.6M |
| United Way of Southeast Missouri | Cape Girardeau | $14,032 | 24 | $1.5M |
| Missouri Incutech Foundation | Rolla | $12,568 | 24 | $1.1M |
| Ascension Foundation | St Louis | $50,000 | 24 | $3.8M |
| Northeast Missouri Area Agency on | Kirksville | $139,925 | 22 | $14.5M |
| Economic Development Corporation of | Kansas City | $10,000 | 22 | $5.7M |
| Foundation for Inclusive Religious Education Inc | Kansas City | $39,999 | 22 | $2.6M |
| Generate Health Stl | Saint Louis | $16,250 | 21 | $1.1M |
| Beta Sigma Phi Charitable Foundation | Kansas City | $10,000 | 21 | $380K |
| Metropolitan Energy Center Inc | Kansas City | $82,699 | 21 | $6.6M |
| Ascension Providence Hospital | St Louis | $20,000 | 20 | $11.5M |